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Organic Chemistry I

Credits 6
Hours per week 2 / 2 / 0
Examination C+Ex
Study Language English
Level Bachelor subject
Guarantor prof. Ing. Jaroslav Kvíčala, CSc.

Summary

In the frame of the structure - reactivity concept,the structure and reactivity of alkanes, alkenes, alkynes, arenes and their monofunctional derivatives: haloalkanes, alcohols and phenols, carbonyl compounds, carboxylic acids and their functional derivatives will be presented.

Syllabus

1. Basic principles of bonding, classification of organic compounds
2. Oxidation number, cation, anions and radicals, electronic effects
3. Alkanes and cycloalkanes, radical substitution
4. Alkenes, electrophilic and radical addition, reduction and oxidation
5. Alkynes, electrophilic and radical addition, reduction, acetylides
6. Isomers, stereochemistry, Fischer projection formula
7. Haloalkanes, monomolecular and bimolecular nucleophilic substitution
8. Haloalkanes, monomolecular and bimolecular elimination
9. Organolithium and organomagnesium compounds, reactivity, organocuprates
10. Conjugated systems, dienes, 1,2- and 1,4-addition, Diels-Alder reaction
11. Arenes, aromaticity, electrophilic substitution
12. Alcohols and phenols, oxonium salts, alcoholates, ethers, amines
13. Carbonyl compounds, acetals, nucleophilic addition
14. Carboxylic acids, acidity, acyl halides, esters, tetrahedral nucleophilic substitution

Literature

Z: Svoboda a kol.: Organická chemie I, Nakladatelství VŠCHT, 2005. 8070805617
Z: J. McMurry: Organická chemie, český překlad 6. vydání, VUT Brno, VŠCHT Praha, 2007. 9788070806371

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