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Data for 2018/2019

Bioengineering Methods

Credits 4
Hours per week 2 / 1 / 0
Examination Ex
Study Language English
Level Master subject
Guarantor prof. Ing. Igor Schreiber, CSc.


The course is building on the basic knowledge of chemical engineering by the student and develops applications in bioengineering. Basic approaches including mass and energy balances, transport processes and reaction kinetics are synthesized to provide quantitative description of processes used in bioengineering. Special attention is given to reaction-transport processes in enzyme reactors and reactors with living cultures of microorganisms.


1. Enzyme catalysis, thermodynamics of enzyme reactions, limitin cases
2. Enzyme reactors, mathematical models and their analysis
3. Immobilized enzymes, effects of mass transport
4. Effectiveness factor, Damköhler number, analysis of heterogeneous enz. systems
5. Microbial growth, stoichiometry of growth, product formation
6. Growth in batch systems
7. Growth in continual systems
8. Structured vs unstructured models of growth
9. Construction and operation of some fermentor types
10. Stirring and aeration
11. Mixed microbial cultures and their interaction
12. Chemostat dynamics with mixed cultures
13. Operating conditions, scale-up
14. Metabolic engineering, metabolic networks


Z: Shuler M. L., Kargi F., Bioprocess Engineering. Basic Concepts, Prentice Hall, Upper Saddle River, 2002, 0-13-081908-5
D: Blanch H. W., Clark D. S., Biochemical Engineering,CRC Taylor and Francis, Boca Raton, 1997, 0-8247-0099-6

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Technická 5
166 28 Prague 6 – Dejvice
IČO: 60461373
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